abstract：:Live Merkel cells in the skin and hair follicles are known to incorporate a fluorescence dye, quinacrine, which has been utilized to identify and dissect the cells for experiments. Quinacrine fluorescence of the cells is, however, quickly lost and quinacrine-stained Merkel cells soon become difficult to identify in ti...

journal_title：Cell and tissue research

authors： Fukuda J,Ishimine H,Masaki Y

更新日期：2003-03-01 00:00:00

abstract：:Cestodes (tapeworms) are a derived, parasitic clade of the phylum Platyhelminthes (flatworms). The cestode body wall represents an adaptation to its endoparasitic lifestyle. The epidermis forms a non-ciliated syncytium, and both muscular and nervous system are reduced. Morphological differences between cestodes and fr...

journal_title：Cell and tissue research

authors： Hartenstein V,Jones M

更新日期：2003-03-01 00:00:00

abstract：:The protein synthesis inhibitor cycloheximide (Chx) suppresses prolactin-induced beta-casein gene expression in the mammary epithelial cell line COMMA-D. As the mechanism underlying this effect is unclear, the effects of protein synthesis inhibitors on interactions of transcription factors with the beta-casein promote...

journal_title：Cell and tissue research

authors： Beaton A,Broadhurst MK,Wilkins RJ,Wheeler TT

更新日期：2003-02-01 00:00:00

abstract：:Cholinergic neurons have been revealed in the enteric nervous system by functional and biochemical studies but not by antibodies that provide excellent localisation of the synthesising enzyme, choline acetyltransferase (ChAT), in the central nervous system. In order to determine whether a newly described peripheral fo...

journal_title：Cell and tissue research

authors： Chiocchetti R,Poole DP,Kimura H,Aimi Y,Robbins HL,Castelucci P,Furness JB

更新日期：2003-01-01 00:00:00

abstract：:Electron-dense granules (EDGs) are singular structures found in the tissues of several vertebrate and invertebrate organisms. Two types of EDGs were observed in hepatopancreatic cells of the crab Ucides cordatus: (1) a non-mineralized EDG, found mainly inside vacuoles, which reacted positively to acid phosphatase and ...

journal_title：Cell and tissue research

authors： Corrêa Junior JD,Allodi S,Farina M

更新日期：2003-01-01 00:00:00

abstract：:Since the advent of transmission electron microscopy of tissues capable of growth and regeneration, cell and developmental biologists have postulated that the undifferentiated cells observed within these tissues represent tissue-specific stem or progenitor cells. However, no studies have addressed the issue of whether...

journal_title：Cell and tissue research

authors： Smith GH,Strickland P,Daniel CW

更新日期：2002-12-01 00:00:00

abstract：:Brain injuries trigger physiological reactions which are mediated by a number of cytokines including interleukin-6 (IL-6), ciliary neurotrophic factor (CNTF), and leukemia inhibitory factor (LIF). Astrocytes and microglia, the protagonists in these traumatic responses, are known to secrete a variety of paracrine signa...

journal_title：Cell and tissue research

authors： Mey J,Henkes L

更新日期：2002-11-01 00:00:00

abstract：:Previous studies have indicated the importance of basement membrane components both for cellular differentiation in general and for the barrier properties of cerebral microvascular endothelial cells in particular. Therefore, we have examined the expression of basement membrane proteins in primary capillary endothelial...

journal_title：Cell and tissue research

authors： Tilling T,Engelbertz C,Decker S,Korte D,Hüwel S,Galla HJ

更新日期：2002-10-01 00:00:00

abstract：:Western Blot and immunohistochemical studies were conducted in the sea pansy Renilla koellikeri, a representative of the earliest multicellular animals with a nervous system, using various antibodies raised against enzymes of the catecholamine biosynthetic pathway. Western blots of sea pansy extracts revealed a protei...

journal_title：Cell and tissue research

authors： Anctil M,Hurtubise P,Gillis MA

更新日期：2002-10-01 00:00:00

abstract：:The motility patterns of the reticulorumen evoke mainly mixing of the ingesta. So far unknown, intrinsic neural circuits of the enteric nervous system are involved in the control of these motility patterns. The aim of the study was to characterize neurochemically sheep ruminal myenteric neurones, in particular the neu...

journal_title：Cell and tissue research

authors： Pfannkuche H,Schemann M,Gäbel G

更新日期：2002-09-01 00:00:00

abstract：:Vesicular transport involves SNARE (soluble- N-ethylmaleimide-sensitive-factor-attachment-protein-receptor) proteins on transport vesicles and on target membranes. Syntaxin 13 is a SNARE enriched in brain, associated with recycling endosomes; its overexpression in PC12 cells promotes neurite outgrowth. This suggests a...

journal_title：Cell and tissue research

authors： Sarria JC,Catsicas S,Hornung JP,Hirling H

更新日期：2002-08-01 00:00:00

abstract：:Intercellular communication between smooth muscle cells is crucial for contractile behaviour in normal and pathologically altered urinary bladder. Since the study of coupling is difficult in situ, we established cell cultures of bladder smooth muscle cells to analyse coupling mechanisms. Microinjection of Lucifer yell...

journal_title：Cell and tissue research

authors： Neuhaus J,Wolburg H,Hermsdorf T,Stolzenburg JU,Dorschner W

更新日期：2002-08-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) contains a biological clock that generates timing signals that drive daily rhythms in behaviors and homeostatic functions. In addition to this pacemaker function, the SCN gates its own sensitivity to incoming signals, which permits appropriate temporal adjustment to achieve synchrony ...

journal_title：Cell and tissue research

authors： Gillette MU,Mitchell JW

更新日期：2002-07-01 00:00:00

abstract：:High-density cultures are widely used as an in vitro model for studies of embryonic cartilage formation. In the present study we investigated the suitability of high-density cultures for the redifferentiation of dedifferentiated chondrocytes. When primary human chondrocytes were cultured in alginate beads, some cells ...

journal_title：Cell and tissue research

authors： Schulze-Tanzil G,de Souza P,Villegas Castrejon H,John T,Merker HJ,Scheid A,Shakibaei M

更新日期：2002-06-01 00:00:00

abstract：:Seven isoforms of tachykinin-related peptides (TRPs) have been isolated from the brain of the cockroach Leucophaea maderae. These peptides (LemTRP-1, 2, and 5-9) share the C-terminal sequence GFX(1)GX(2)Ramide (where X(1) and X(2) are variable residues). In order to determine the neuronal distribution of several of th...

journal_title：Cell and tissue research

authors： Nässel DR,Winther AM

更新日期：2002-05-01 00:00:00

abstract：:Intercellular bridges (IBs) connecting the cytoplasms of a defined type of defective germ cell division ("arrested mitoses") in male and female gonads of the immature golden hamster were studied by electron microscopy. In both sexes, such cells appear at the time when germ cells switch from mitotic proliferation to th...

journal_title：Cell and tissue research

authors： Miething A

更新日期：2002-04-01 00:00:00

abstract：:Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...

journal_title：Cell and tissue research

authors： Fisher JL,Schmitt JF,Howard ML,Mackie PS,Choong PF,Risbridger GP

更新日期：2002-03-01 00:00:00

abstract：:The glucose transporter 8 (GLUT8) is a recently identified member of the family of sugar transport facilitators. In human tissues GLUT8 is predominantly expressed in testis in a gonadotropin-dependent manner. It is shown here that the onset of mRNA synthesis of GLUT8 during the maturation of mouse testis coincides wit...

journal_title：Cell and tissue research

authors： Schürmann A,Axer H,Scheepers A,Doege H,Joost HG

更新日期：2002-02-01 00:00:00

abstract：:A major difficulty in the investigation of interstitial cells of Cajal (ICC) is in identifying these cells within intact, living gastrointestinal tissues. To overcome this difficulty we developed a method to visualize ICC in the myenteric plexus region (ICC-MP) of the guinea pig ileum. Cells were identified with Nomar...

journal_title：Cell and tissue research

authors： Belzer V,Kobilo T,Rich A,Hanani M

更新日期：2002-01-01 00:00:00

abstract：:Sites of synthesis and release patterns of crustacean hyperglycaemic hormone precursor-related peptide (CPRP) were investigated with those of crustacean hyperglycaemic hormone (cHH), in order to determine whether this precursor-related peptide satisfies certain criteria necessary for its definition as a secretable, ci...

journal_title：Cell and tissue research

authors： Wilcockson DC,Chung SJ,Webster SG

更新日期：2002-01-01 00:00:00

abstract：:Bullous pemphigoid antigen-1 (BPA1) and alpha(6)beta(4)-integrin colocalize at the hemidesmosomes in basal-layer keratinocytes of normal squamous epithelia. The expression of these genes was analyzed during the process of tumor cell invasion and metastasis on frozen sections of head and neck biopsies, and the structur...

journal_title：Cell and tissue research

authors： Herold-Mende C,Kartenbeck J,Tomakidi P,Bosch FX

更新日期：2001-12-01 00:00:00

abstract：:Besides its function at cholinergic synapses, acetylcholinesterase (AChE) exerts structural functions on neural differentiation, independent of its enzymatic activity. To elucidate such functions, we have previously heterologously expressed AChE in histotypic retinal reaggregates, revealing strong effects on their his...

journal_title：Cell and tissue research

authors： Keller M,Robitzki A,Layer PG

更新日期：2001-11-01 00:00:00

abstract：:We conducted an immunoelectron-microscopic study for histamine (HA) in the enterochromaffin-like (ECL) cells of normal rats and rats given alpha-fluoromethylhistidine (alpha-FMH, 3 mg/kg per hour) via osmotic minipumps over a period of 24 h. The indirect immunoperoxidase procedure utilized a mouse monoclonal antibody ...

journal_title：Cell and tissue research

authors： Fujiwara K,Karasuyama M,Murata I,Tanabe T,Yabuuchi M,Inoue Y,Tsuru D

更新日期：2001-11-01 00:00:00

abstract：:Interstitial cells of Cajal (ICC) are important regulatory cells in the smooth muscle coats of the digestive tract. Expression of the Kit receptor tyrosine kinase was used in this study as a marker to study their distribution and development in the striated musculature of the mouse esophagus. Sections and whole-mounts...

journal_title：Cell and tissue research

authors： Rumessen JJ,de Kerchove d'Exaerde A,Mignon S,Bernex F,Timmermans JP,Schiffmann SN,Panthier JJ,Vanderwinden JM

更新日期：2001-10-01 00:00:00

abstract：:The ontogeny of gut innervation in the anuran amphibian Xenopus laevis was studied using immunohistochemistry on sections of whole larvae from NF stages 38-52. Immunoreactivity to acetylated tubulin confirmed the presence of nerve fibres as early as stages 38-39. Actin immunoreactivity was found at stage 41, indicatin...

journal_title：Cell and tissue research

authors： Holmberg A,Hägg U,Fritsche R,Holmgren S

更新日期：2001-10-01 00:00:00

abstract：:Nerve growth factor (NGF) induces morphological and physiological changes in cultured pancreatic beta-cells, including the extension of neurite-like processes. This latter effect is potentiated by dibutyryl cAMP (dbcAMP). beta-cells cultured under these conditions maintain their immunoreactivity to insulin and gamma-a...

journal_title：Cell and tissue research

authors： González del Pliego M,Aguirre-Benítez E,Sánchez-Soto MC,Larrieta ME,Velázquez-Carranza A,Vidaltamayo R,Meza-Mora M,Zepeda-Rodríguez A,Hernández-Falcón J,Hiriart M

更新日期：2001-09-01 00:00:00

abstract：:Neurotrophins signal via a dual-receptor system comprising receptor tyrosine kinases, the Trks, and a tumor necrosis factor (TNF) receptor like molecule, p75. Interest in these receptors was spurred on by the finding that they are employed by their neurotrophin ligands to activate opposing cellular mechanisms. Signall...

journal_title：Cell and tissue research

authors： Dechant G

更新日期：2001-08-01 00:00:00

abstract：:Previous studies have identified Dogiel type II neurons with cell bodies in the myenteric plexus of guinea-pig ileum to be intrinsic primary afferent neurons. These neurons also have distinctive electrophysiological characteristics (they are AH neurons) and 82-84% are immunoreactive for calbindin. They are the only ca...

journal_title：Cell and tissue research

authors： Quinson N,Robbins HL,Clark MJ,Furness JB

更新日期：2001-07-01 00:00:00

abstract：:The origin of cobblestone-like polygonal cells (the most numerous in renal glomerular cell culture) remains controversial; they could be either dedifferentiated podocytes or parietal epithelial cells (PECs) of Bowman's capsule. Poor cellular outgrowth from glomeruli devoid of Bowman's capsule (decapsulated glomeruli) ...

journal_title：Cell and tissue research

authors： Yaoita E,Kurihara H,Sakai T,Ohshiro K,Yamamoto T

更新日期：2001-06-01 00:00:00

abstract：:This study describes the morphology and distribution of setae on the lateral and medial flagella of the antennules of the spiny lobster Panulirus argus in an effort to identify antennular chemoreceptors in addition to the well-studied aesthetasc chemosensilla. Setae were examined using light and electron microscopy, a...

journal_title：Cell and tissue research

authors： Cate HS,Derby CD

更新日期：2001-06-01 00:00:00

abstract：:Expression of the non-muscle myosin heavy chain-B (NM-MHC-B, also denoted as the embryonic smooth muscle myosin heavy chain, SMemb) was examined in rat urinary bladder during growth in response to a partial urinary outflow obstruction. Following obstruction, the weight of the urinary bladder increased more than five-f...

journal_title：Cell and tissue research

authors： Sjuve R,Haase H,Ekblad E,Malmqvist U,Morano I,Arner A

更新日期：2001-05-01 00:00:00

abstract：:The function of exocytosis during plasma membrane resealing might be to facilitate the flow of surface lipid over the disruption site and/or to add defect-spanning "patches" of internal membrane across it. Scanning-electron-microscopic visualization of large plasma membrane disruptions in sea urchin eggs is here used ...

journal_title：Cell and tissue research

authors： McNeil PL,Baker MM

更新日期：2001-04-01 00:00:00

abstract：:The distribution of the glycoprotein, mucin 1 (MUC1), was determined in lactating guinea-pig mammary tissue at the resolution of the electron microscope. MUC1 was detected on the apical plasma membrane of secretory epithelial cells, the surface of secreted milk-fat globules, the limiting membranes of secretory vesicle...

journal_title：Cell and tissue research

authors： Mather IH,Jack LJ,Madara PJ,Johnson VG

更新日期：2001-04-01 00:00:00

abstract：:The tyrosine kinase proteins (Trk), encoded by the trk family of proto-oncogenes, mediate, in mammals, the action of neurotrophins, a family of growth factors acting on the development and maintenance of the nervous system. Neurotrophins and their specific receptors, TrkA, TrkB and TrkC, seem to be phylogenetically we...

journal_title：Cell and tissue research

authors： Lucini C,de Girolamo P,Lamanna C,Botte V,Vega JA,Castaldo L

更新日期：2001-03-01 00:00:00

abstract：:Changes in the frequency of endocrine cells are evidence of intestinal adaptation to germ-free (GF) status. Not only the distribution of these cells along the intestine, but also the differences in intracellular content of these regulatory peptides may be explored to explain functional and structural aspects of GF int...

journal_title：Cell and tissue research

authors： Arantes RM,Nogueira AM

更新日期：2001-03-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) is a recently discovered isoform of cyclooxygenase that is inducible by various types of inflammatory stimuli. Although this enzyme is considered to play a major role in inflammation processes by catalyzing the production of prostaglandins, the precise location, distribution, and regulation of...

journal_title：Cell and tissue research

authors： Ichitani Y,Holmberg K,Maunsbach AB,Haeggström JZ,Samuelsson B,De Witt D,Hökfelt T

更新日期：2001-02-01 00:00:00

abstract：:Molting in shrimp is controlled by the molt-inhibiting hormone (MIH) and ecdysone. MIH inhibits the synthesis of ecdysone in the Y-organ, resulting in molt suppression; it is a neuropeptide member belonging to the eyestalk CHH/MIH/GIH family. The cloning of MIH (formerly MIH-like) of the shrimp Metapenaeus ensis has b...

journal_title：Cell and tissue research

authors： Gu PL,Chu KH,Chan SM

更新日期：2001-01-01 00:00:00

abstract：:The fiber arrangement of the retinogeniculate pathways was investigated in the Japanese monkey chiasm by iontophoretical injections into the lateral geniculate nucleus of wheat germ agglutinin conjugated to horseradish peroxidase. The present data demonstrated that the horizontal and dorsoventral axes of the nasal ret...

journal_title：Cell and tissue research

authors： Naito J

更新日期：2000-12-01 00:00:00

abstract：:In the chironomid Acricotopus lucidus, germ line-soma differentiation becomes evident with the formation of the pole cells and the elimination of the germ line-limited chromosomes (Ks) from the future somatic nuclei of the embryo. Unlike in Drosophila, the early nuclear divisions do not proceed synchronously in A. luc...

journal_title：Cell and tissue research

authors： Staiber W

更新日期：2000-11-01 00:00:00

abstract：:Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...

journal_title：Cell and tissue research

authors： Spicer SS,Salvi RJ,Schulte BA

更新日期：2000-10-01 00:00:00